Professor Onishi Motoko from the Department of Applied Biochemistry, Department of Applied Biology, Chubu University, Japan, and others cooperated with San-ei Sucrochemical, a saccharified product company that produces glucose and other saccharification products, and found through human clinical trials that indigestible oligosaccharides possess both sugar and acid properties. "Maltobionska kislina" inhibits the loss of collagen components in bones and helps maintain bone components.
About five years ago, the research team looked at the "maltonic acid" contained in honey, which people have been eating since ancient times, and evaluated its effect on maintaining bone health. In the evaluation experiment, the research team first performed cell experiments using bone marrow cells collected from mouse femurs and found that adding maltonic acid to the cells inhibited osteoclast differentiation. Then, animal experiments were conducted, and after feeding the ovariectomized postmenopausal model mice with a diet containing maltonic acid for 80 consecutive days, it was confirmed that calcium loss and bone density in the femur were significantly suppressed compared with mice fed a diet without maltonic acid. decline.
Da bi preverili učinek na človeško telo, so izvedli tudi klinično preskušanje pri ljudeh, v katerem so zaposlene na univerzi Chubu, stare od 40 do 60 let, 4 tedne zapored zaužile 4 g zrnc, ki vsebujejo maltonsko kislino. Rezultati so pokazali, da se je pri 33 moških v menopavzi za več kot 1 leto izločanje kolagenskih komponent (DPD, u-NTx, indikatorji resorpcije kosti) iz kosti (DPD, u{5}}NTx) v več kot 1 letu bistveno zmanjšalo. pred zaužitjem maltonske kisline. , dolgotrajen vnos maltonske kisline je zaviral izgubo kosti. Poleg tega je maltonska kislina neprebavljiv oligosaharid, zato je to klinično preskušanje potrdilo, da maltonska kislina vpliva tudi na izboljšanje odvajal in uravnavanje stanja prebavil.
Flavia
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